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- B5bc3d0b21e7a182428a5c6ad4b38098b NCIT_P378 "NCI" @default.
- B5bc3d0b21e7a182428a5c6ad4b38098b type Axiom @default.
- B5bc3d0b21e7a182428a5c6ad4b38098b annotatedProperty IAO_0000115 @default.
- B5bc3d0b21e7a182428a5c6ad4b38098b annotatedSource NCIT_C907 @default.
- B5bc3d0b21e7a182428a5c6ad4b38098b annotatedTarget "A therapeutic formulation of the primary physiologically active form of endogenous thyroid hormone. In vivo, triiodothyronine enters the nucleus and binds to nuclear thyroid hormone receptors that subsequently bind to thyroid response elements (TREs) located in target genes. Receptor binding by triiodothyronine in combination with recruited coactivators results in maximal transcriptional activation after binding to TREs; in general, binding of thyroid hormone receptor alone to TREs leads to repression of gene transcription (NCI04)" @default.