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- B5bf178e5725c169b0054f15034dfe8d0 NCIT_P378 "NCI" @default.
- B5bf178e5725c169b0054f15034dfe8d0 type Axiom @default.
- B5bf178e5725c169b0054f15034dfe8d0 annotatedProperty IAO_0000115 @default.
- B5bf178e5725c169b0054f15034dfe8d0 annotatedSource NCIT_C1844 @default.
- B5bf178e5725c169b0054f15034dfe8d0 annotatedTarget "An ester analog of rapamycin. Temsirolimus binds to and inhibits the mammalian target of rapamycin (mTOR), resulting in decreased expression of mRNAs necessary for cell cycle progression and arresting cells in the G1 phase of the cell cycle. mTOR is a serine/threonine kinase which plays a role in the PI3K/AKT pathway that is upregulated in some tumors." @default.