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- B5c1510ea6b4d0fba8fa8bd063a707932 NCIT_P378 "NCI" @default.
- B5c1510ea6b4d0fba8fa8bd063a707932 type Axiom @default.
- B5c1510ea6b4d0fba8fa8bd063a707932 annotatedProperty IAO_0000115 @default.
- B5c1510ea6b4d0fba8fa8bd063a707932 annotatedSource NCIT_C1178 @default.
- B5c1510ea6b4d0fba8fa8bd063a707932 annotatedTarget "A pan-nitric oxide synthase (NOS) inhibitor, with potential immunomodulating and antineoplastic activities. Upon administration, tilarginine binds to and inhibits NOS, a free radical signaling molecule that promotes angiogenesis, metastasis, and immunosuppression in the tumor microenvironment (TME). Reduction in NOS activity may abrogate the immunosuppressive TME, enhance tumor antigen-specific immune response and inhibit tumor cell proliferation." @default.