Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B5dd90efb877e5b1e004b15b4b84b3d3c> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B5dd90efb877e5b1e004b15b4b84b3d3c NCIT_P378 "NCI" @default.
- B5dd90efb877e5b1e004b15b4b84b3d3c type Axiom @default.
- B5dd90efb877e5b1e004b15b4b84b3d3c annotatedProperty IAO_0000115 @default.
- B5dd90efb877e5b1e004b15b4b84b3d3c annotatedSource NCIT_C182008 @default.
- B5dd90efb877e5b1e004b15b4b84b3d3c annotatedTarget "An orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities. Upon oral administration, Bcl-2 inhibitor TQB3909 targets, binds to and inhibits the activity of Bcl-2. This restores caspase-mediated apoptosis in tumor cells. Bcl-2 is overexpressed in many cancers and plays an important role in the negative regulation of apoptosis. Its expression is associated with increased drug resistance and tumor cell survival." @default.