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- B5e0f5bf7e24d4c4027641e5552e0bfcc NCIT_P378 "NCI" @default.
- B5e0f5bf7e24d4c4027641e5552e0bfcc type Axiom @default.
- B5e0f5bf7e24d4c4027641e5552e0bfcc annotatedProperty IAO_0000115 @default.
- B5e0f5bf7e24d4c4027641e5552e0bfcc annotatedSource NCIT_C27080 @default.
- B5e0f5bf7e24d4c4027641e5552e0bfcc annotatedTarget "Refractory anemia with excess blasts in transformation (RAEB-T) is characterised by dysplastic features of the myeloid and usually erythroid progenitor cells in the bone marrow and an increased number of myeloblasts in the peripheral blood. The peripheral blood blast count ranges from 20% to 30%. RAEB-T used to be a subcategory of myelodysplastic syndromes in the past. Recently, the term has been eliminated from the WHO based classification of myelodysplastic syndromes. The reason is that the percentage of peripheral blood blasts required for the diagnosis of acute myeloid leukemia has been reduced to 20%. The elimination of the RAEB-T term by the WHO experts has created confusion and ongoing arguments. Currently, according to WHO classification, the vast majority of RAEB-T cases are best classified as acute leukemias (acute leukemias with multilineage dysplasia following myelodysplastic syndrome). A minority of cases are part of RAEB-2." @default.