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- B5e34a30df40d84a1c4d8423efcf626ac NCIT_P378 "NCI" @default.
- B5e34a30df40d84a1c4d8423efcf626ac type Axiom @default.
- B5e34a30df40d84a1c4d8423efcf626ac annotatedProperty IAO_0000115 @default.
- B5e34a30df40d84a1c4d8423efcf626ac annotatedSource NCIT_C80682 @default.
- B5e34a30df40d84a1c4d8423efcf626ac annotatedTarget "The mesylate salt of an orally active small molecule with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines." @default.