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- B5ea1d5f91250546f38e4b1267ceaa767 NCIT_P378 "NCI" @default.
- B5ea1d5f91250546f38e4b1267ceaa767 type Axiom @default.
- B5ea1d5f91250546f38e4b1267ceaa767 annotatedProperty IAO_0000115 @default.
- B5ea1d5f91250546f38e4b1267ceaa767 annotatedSource NCIT_C51124 @default.
- B5ea1d5f91250546f38e4b1267ceaa767 annotatedTarget "Human SRC wild-type allele is located within 20q12-q13 and is approximately 61 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase Src protein, plays a role in signal transduction pathways involved in the inhibition of endothelial cell apoptosis, regulation of the actin cytoskeleton, and the production of gonadotropins in pituitary cells. An allelic variant of the SRC gene, which produces a truncated, inactive protein, is associated with the development and metastasis of both breast and colon cancer." @default.