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- B5f2e249240b17d228dfc3d3d9d57d25a NCIT_P378 "BIOCARTA" @default.
- B5f2e249240b17d228dfc3d3d9d57d25a type Axiom @default.
- B5f2e249240b17d228dfc3d3d9d57d25a annotatedProperty NCIT_P325 @default.
- B5f2e249240b17d228dfc3d3d9d57d25a annotatedSource NCIT_C39118 @default.
- B5f2e249240b17d228dfc3d3d9d57d25a annotatedTarget "Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor for IL-17 is widely expressed throughout the body, including fibroblasts and epithelial cells. Inflammatory responses involving IL-17 probably contribute to arthritis, asthma, skin immune reactions, and autoimmune disorders. Fibroblasts and other cells stimulated by IL-17 are induced themselves to secrete inflammatory and hematopoietic cytokines, including IL-6, IL-8, G-CSF, and Stem Cell Factor (SCF). These cytokines in turn provoke a range of activities, including the stimulation of neutrophil proliferation and differentiation. (This definition may be outdated - see the DesignNote.)" @default.