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- B5fe5e0bfad36226aa3e4d416cc1c9e41 NCIT_P378 "NCI" @default.
- B5fe5e0bfad36226aa3e4d416cc1c9e41 type Axiom @default.
- B5fe5e0bfad36226aa3e4d416cc1c9e41 annotatedProperty IAO_0000115 @default.
- B5fe5e0bfad36226aa3e4d416cc1c9e41 annotatedSource NCIT_C80377 @default.
- B5fe5e0bfad36226aa3e4d416cc1c9e41 annotatedTarget "A transdermal system containing granisetron, a selective serotonin (5-HT) receptor antagonist, with antiemetic activity. Upon application of the transdermal patch to the skin and subsequent release into the bloodstream, granisetron selectively binds to and blocks the 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS). By preventing stimulation of 5-HT3 receptors, this agent is able to suppress chemotherapy-induced nausea and vomiting." @default.