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- B610840743006b4186cde96ac358f71a4 NCIT_P378 "NCI" @default.
- B610840743006b4186cde96ac358f71a4 type Axiom @default.
- B610840743006b4186cde96ac358f71a4 annotatedProperty IAO_0000115 @default.
- B610840743006b4186cde96ac358f71a4 annotatedSource NCIT_C152913 @default.
- B610840743006b4186cde96ac358f71a4 annotatedTarget "The sulfate salt form of vorapaxar, an orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic." @default.