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- B614fa842d279cb266b10831471a3a4d6 NCIT_P378 "NCI" @default.
- B614fa842d279cb266b10831471a3a4d6 type Axiom @default.
- B614fa842d279cb266b10831471a3a4d6 annotatedProperty IAO_0000115 @default.
- B614fa842d279cb266b10831471a3a4d6 annotatedSource NCIT_C61902 @default.
- B614fa842d279cb266b10831471a3a4d6 annotatedTarget "The acetate salt form of pramlintide, a peptide analogue of human amylin with 3 proline substitutions at position 25, 28 and 29, with antihyperglycemic activity. By mimicking amylin, pramlintide slows gastric emptying, inhibits digestive secretions (gastric acid, pancreatic enzymes, and bile), reduces glucagon secretion, and increases satiety; all of these actions are mediated mostly by glucose-sensitive areas in the brain stem. The overall result is a decrease in blood glucose levels. The use of pramlintide may cause an increased risk of insulin-induced hypoglycemia." @default.