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- B624c68805bc17dfc6945edcbb1a64422 NCIT_P378 "NCI" @default.
- B624c68805bc17dfc6945edcbb1a64422 type Axiom @default.
- B624c68805bc17dfc6945edcbb1a64422 annotatedProperty IAO_0000115 @default.
- B624c68805bc17dfc6945edcbb1a64422 annotatedSource NCIT_C61933 @default.
- B624c68805bc17dfc6945edcbb1a64422 annotatedTarget "The calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol." @default.