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- B6292bcbfabbb6774e08cfe6a5095955c NCIT_P378 "NCI" @default.
- B6292bcbfabbb6774e08cfe6a5095955c type Axiom @default.
- B6292bcbfabbb6774e08cfe6a5095955c annotatedProperty IAO_0000115 @default.
- B6292bcbfabbb6774e08cfe6a5095955c annotatedSource NCIT_C2714 @default.
- B6292bcbfabbb6774e08cfe6a5095955c annotatedTarget "A murine monoclonal antibody targeting the epidermal growth factor receptor (EGFR) exhibiting anti-tumor activity. EMD 55900 antibody binds to the extracellular domain of EGFR close to the EGF binding domain and does not induce any tyrosine kinase activity on its own. As a result, EMD 55900 binding inhibits receptor activation by natural ligands thereby interrupting activation of downstream signaling cascade, required for tumor cell growth and proliferation." @default.