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- B64eaf50f11f3a269ff47a876c7373eb5 NCIT_P378 "NCI" @default.
- B64eaf50f11f3a269ff47a876c7373eb5 type Axiom @default.
- B64eaf50f11f3a269ff47a876c7373eb5 annotatedProperty IAO_0000115 @default.
- B64eaf50f11f3a269ff47a876c7373eb5 annotatedSource NCIT_C224 @default.
- B64eaf50f11f3a269ff47a876c7373eb5 annotatedTarget "A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies. (NCI04)" @default.