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- B6670ae9d7ed37712bb4b1477ab72800f NCIT_P378 "NCI" @default.
- B6670ae9d7ed37712bb4b1477ab72800f type Axiom @default.
- B6670ae9d7ed37712bb4b1477ab72800f annotatedProperty IAO_0000115 @default.
- B6670ae9d7ed37712bb4b1477ab72800f annotatedSource NCIT_C104005 @default.
- B6670ae9d7ed37712bb4b1477ab72800f annotatedTarget "A biosimilar of pegfilgrastim, a long-acting pegylated form of recombinant human granulocyte colony-stimulating factor (G-CSF) filgrastim, with hematopoietic activity. In a similar manner to G-CSF, pegfilgrastim biosimilar LA-EP2006 binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Therefore, this agent may prevent the incidence and shorten the duration of chemotherapy-induced neutropenia. Conjugation of the cytokine with a branched polyethylene glycol molecule significantly increases this agent's therapeutic half-life compared to filgrastim." @default.