Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B668b5ab9c7a6000d16e5d1109c13b9ed> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B668b5ab9c7a6000d16e5d1109c13b9ed NCIT_P378 "KEGG" @default.
- B668b5ab9c7a6000d16e5d1109c13b9ed type Axiom @default.
- B668b5ab9c7a6000d16e5d1109c13b9ed annotatedProperty NCIT_P325 @default.
- B668b5ab9c7a6000d16e5d1109c13b9ed annotatedSource NCIT_C91457 @default.
- B668b5ab9c7a6000d16e5d1109c13b9ed annotatedTarget "Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates." @default.