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- B6725b2c89eebd2325b5e74caff705e3f NCIT_P378 "NCI" @default.
- B6725b2c89eebd2325b5e74caff705e3f type Axiom @default.
- B6725b2c89eebd2325b5e74caff705e3f annotatedProperty IAO_0000115 @default.
- B6725b2c89eebd2325b5e74caff705e3f annotatedSource NCIT_C178439 @default.
- B6725b2c89eebd2325b5e74caff705e3f annotatedTarget "A preparation of T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the human tumor-associated antigen (TAA) mesothelin (MSLN), with potential immunomodulating and antineoplastic activities. Upon administration, the anti-MSLN CAR-T cells LCAR-M23 specifically target and kill MSLN-expressing tumor cells. Mesothelin, a cell surface glycoprotein involved in cell adhesion, is overexpressed in a variety of cancer cell types." @default.