Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B680874d6aea1117e814518734a93ec0f> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B680874d6aea1117e814518734a93ec0f NCIT_P378 "NCI" @default.
- B680874d6aea1117e814518734a93ec0f type Axiom @default.
- B680874d6aea1117e814518734a93ec0f annotatedProperty IAO_0000115 @default.
- B680874d6aea1117e814518734a93ec0f annotatedSource NCIT_C28862 @default.
- B680874d6aea1117e814518734a93ec0f annotatedTarget "The hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.