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- B68198f71a6dc898a9c6de74d8e76f1eb NCIT_P378 "NCI" @default.
- B68198f71a6dc898a9c6de74d8e76f1eb type Axiom @default.
- B68198f71a6dc898a9c6de74d8e76f1eb annotatedProperty IAO_0000115 @default.
- B68198f71a6dc898a9c6de74d8e76f1eb annotatedSource NCIT_C2062 @default.
- B68198f71a6dc898a9c6de74d8e76f1eb annotatedTarget "An orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities. LGD 1550 selectively binds to all three retinoic acid receptors (RAR-alpha, RAR-beta, and RAR-gamma), resulting in alterations in the expression of genes responsible for cell differentiation and proliferation. This agent also acts as an inhibitor of activator protein 1 (AP-1), a protein that mediates trophic responses and malignant transformation. (NCI04)" @default.