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- B68379c3ffc99d000281b009d1028959f hasDbXref "NCIT:P378" @default.
- B68379c3ffc99d000281b009d1028959f type Axiom @default.
- B68379c3ffc99d000281b009d1028959f annotatedProperty IAO_0000115 @default.
- B68379c3ffc99d000281b009d1028959f annotatedSource MONDO_0002083 @default.
- B68379c3ffc99d000281b009d1028959f annotatedTarget "Transformation of chronic lymphocytic leukemia into aggressive non-Hodgkin's lymphoma, usually diffuse large B-cell lymphoma (immunoblastic or centroblastic variant). Occasional cases of transformation to Hodgkin's lymphoma have also been described, particularly in patients treated with purine nucleotide analogs. Molecular genetic studies suggest that in approximately half of the cases, the lymphoma is clonally related to the underlying chronic lymphocytic leukemia, whereas in the remaining cases the lymphoma probably represents a secondary, unrelated neoplasm." @default.