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- B6842a6bfa7c49063485a62d794327916 NCIT_P378 "NCI" @default.
- B6842a6bfa7c49063485a62d794327916 type Axiom @default.
- B6842a6bfa7c49063485a62d794327916 annotatedProperty IAO_0000115 @default.
- B6842a6bfa7c49063485a62d794327916 annotatedSource NCIT_C117726 @default.
- B6842a6bfa7c49063485a62d794327916 annotatedTarget "A recombinant monoclonal antibody against human epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Upon administration, anti-EGFR monoclonal antibody SCT200 targets EGFR, prevents the activation and subsequent dimerization of this receptor and inhibits both EGFR-mediated signal transduction and cellular proliferation of EGFR-expressing tumor cells. In addition, SCT200 may induce antibody-dependent cell-mediated cytotoxicity (ADCC) against EGFR-expressing tumor cells. EGFR, a member of the epidermal growth factor receptor family, is overexpressed on the cell surfaces of various solid tumors." @default.