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- B6a32ad7c52a8f2d124fbb52eca36aa55 NCIT_P378 "NCI" @default.
- B6a32ad7c52a8f2d124fbb52eca36aa55 type Axiom @default.
- B6a32ad7c52a8f2d124fbb52eca36aa55 annotatedProperty IAO_0000115 @default.
- B6a32ad7c52a8f2d124fbb52eca36aa55 annotatedSource NCIT_C1057 @default.
- B6a32ad7c52a8f2d124fbb52eca36aa55 annotatedTarget "A purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic, antioxidant, and anti-inflammatory activities. Cordycepin is an inhibitor of polyadenylation, activates AMP-activated protein kinase (AMPK) and reduces mammalian target of rapamycin (mTOR) signaling, which may result in both the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR, a serine/threonine kinase belonging to the phosphatidylinositol 3-kinase (PI3K)-related kinase (PIKK) family, plays an important role in the PI3K/AKT/mTOR signaling pathway that regulates cell growth and proliferation, and its expression or activity is frequently dysregulated in human cancers." @default.