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- B6b27415a37fe3e084c04306154e628cb NCIT_P378 "NCI" @default.
- B6b27415a37fe3e084c04306154e628cb type Axiom @default.
- B6b27415a37fe3e084c04306154e628cb annotatedProperty IAO_0000115 @default.
- B6b27415a37fe3e084c04306154e628cb annotatedSource NCIT_C101227 @default.
- B6b27415a37fe3e084c04306154e628cb annotatedTarget "A purine-based heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Zelavespib specifically inhibits active Hsp90, thereby inhibiting its chaperone function and promoting the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may result in the inhibition of cellular proliferation in susceptible tumor cell populations. Hsp90, a molecular chaperone protein, is upregulated in a variety of tumor cell types." @default.