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- B6bf193d8c63f2a60847c629d5ab593ef NCIT_P378 "NCI" @default.
- B6bf193d8c63f2a60847c629d5ab593ef type Axiom @default.
- B6bf193d8c63f2a60847c629d5ab593ef annotatedProperty IAO_0000115 @default.
- B6bf193d8c63f2a60847c629d5ab593ef annotatedSource NCIT_C1054 @default.
- B6bf193d8c63f2a60847c629d5ab593ef annotatedTarget "A semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Clarithromycin has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)" @default.