Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B6ce0392de255d21e4fe717bf8dde6c5f> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B6ce0392de255d21e4fe717bf8dde6c5f NCIT_P378 "NCI" @default.
- B6ce0392de255d21e4fe717bf8dde6c5f type Axiom @default.
- B6ce0392de255d21e4fe717bf8dde6c5f annotatedProperty IAO_0000115 @default.
- B6ce0392de255d21e4fe717bf8dde6c5f annotatedSource NCIT_C156732 @default.
- B6ce0392de255d21e4fe717bf8dde6c5f annotatedTarget "A recombinant, plasmid DNA expression vector encoding a 39 nucleotide (nt) short hairpin RNA (shRNA) specific for the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon intratumoral administration, the EGFR antisense DNA BB-401 is taken up by tumor cells and shRNA is transcribed. The shRNA is converted into small interfering RNA (siRNA) via the RNA interference (RNAi) pathway. The siRNA targets and binds to EGFR RNA expressed by tumor cells. This blocks EGFR mRNA translation and prevents EGFR protein expression." @default.