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- B6db23d7ee50b5801988f82d220db5052 NCIT_P378 "NCI" @default.
- B6db23d7ee50b5801988f82d220db5052 type Axiom @default.
- B6db23d7ee50b5801988f82d220db5052 annotatedProperty IAO_0000115 @default.
- B6db23d7ee50b5801988f82d220db5052 annotatedSource NCIT_C78830 @default.
- B6db23d7ee50b5801988f82d220db5052 annotatedTarget "A cancer vaccine consisting of autologous, mature monocyte-derived dendritic cells (DCs) transfected with oncofetal antigen immature laminin receptor protein (OFA-iLRP) RNA, with potential antineoplastic activity. Upon administration, DCs in the OFA-iLRP RNA-transfected autologous dendritic cell vaccine express, process, and present OFA-iLRP to the host immune system, which may mount a potent cytotoxic T-cell (CTL) response against OFA-iLRP-expressing tumor cells. As a highly conserved protein, OFA-iLRP is preferentially expressed in fetal tissues and in many types of cancer, including hematopoietic malignancies, but is not detectable in normal differentiated adult cells." @default.