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- B6df6e65610541735d0af73dee9dd3d66 NCIT_P378 "NCI" @default.
- B6df6e65610541735d0af73dee9dd3d66 type Axiom @default.
- B6df6e65610541735d0af73dee9dd3d66 annotatedProperty IAO_0000115 @default.
- B6df6e65610541735d0af73dee9dd3d66 annotatedSource NCIT_C1884 @default.
- B6df6e65610541735d0af73dee9dd3d66 annotatedTarget "An orally bioavailable receptor tyrosine kinase inhibitor. SU6668 binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. SU6668 also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. (NCI04)" @default.