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- B6e8c2b01a26e6ecc9f78b90b0439749f NCIT_P378 "NCI" @default.
- B6e8c2b01a26e6ecc9f78b90b0439749f type Axiom @default.
- B6e8c2b01a26e6ecc9f78b90b0439749f annotatedProperty IAO_0000115 @default.
- B6e8c2b01a26e6ecc9f78b90b0439749f annotatedSource NCIT_C82600 @default.
- B6e8c2b01a26e6ecc9f78b90b0439749f annotatedTarget "A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)" @default.