Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B70312396aa8be949cd17b9cf56f05c65> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B70312396aa8be949cd17b9cf56f05c65 NCIT_P378 "NCI" @default.
- B70312396aa8be949cd17b9cf56f05c65 type Axiom @default.
- B70312396aa8be949cd17b9cf56f05c65 annotatedProperty IAO_0000115 @default.
- B70312396aa8be949cd17b9cf56f05c65 annotatedSource NCIT_C733 @default.
- B70312396aa8be949cd17b9cf56f05c65 annotatedTarget "A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha and interferon-gamma, while it induces Th2-like (T-helper 2) cytokine production, thereby inhibiting Th1-mediated (T-helper 1) inflammatory and autoimmune responses." @default.