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- B70f084a59294d8ca845b87365b4d4f4c NCIT_P378 "NCI" @default.
- B70f084a59294d8ca845b87365b4d4f4c type Axiom @default.
- B70f084a59294d8ca845b87365b4d4f4c annotatedProperty IAO_0000115 @default.
- B70f084a59294d8ca845b87365b4d4f4c annotatedSource NCIT_C61797 @default.
- B70f084a59294d8ca845b87365b4d4f4c annotatedTarget "A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including inhibition of biogenic amine uptake, binding to opioid receptors, and inhibition of N-methyl D-aspartate (NMDA) receptors. Because of the involvement of spinal NMDA receptors in the process of central sensitization, this agent may reduce pain perception and induce sedation." @default.