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- B7148d4ca43af99bbdefd08d60f125dd1 NCIT_P378 "NCI" @default.
- B7148d4ca43af99bbdefd08d60f125dd1 type Axiom @default.
- B7148d4ca43af99bbdefd08d60f125dd1 annotatedProperty IAO_0000115 @default.
- B7148d4ca43af99bbdefd08d60f125dd1 annotatedSource NCIT_C62039 @default.
- B7148d4ca43af99bbdefd08d60f125dd1 annotatedTarget "A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04)" @default.