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- B71a4f14d2b1517c88dc1c0555a4b6e2d NCIT_P378 "NCI" @default.
- B71a4f14d2b1517c88dc1c0555a4b6e2d type Axiom @default.
- B71a4f14d2b1517c88dc1c0555a4b6e2d annotatedProperty IAO_0000115 @default.
- B71a4f14d2b1517c88dc1c0555a4b6e2d annotatedSource NCIT_C47530 @default.
- B71a4f14d2b1517c88dc1c0555a4b6e2d annotatedTarget "A propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory." @default.