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- B744b6f3582575a81aa0d38a6cd1bd44e NCIT_P378 "NCI" @default.
- B744b6f3582575a81aa0d38a6cd1bd44e type Axiom @default.
- B744b6f3582575a81aa0d38a6cd1bd44e annotatedProperty IAO_0000115 @default.
- B744b6f3582575a81aa0d38a6cd1bd44e annotatedSource NCIT_C179274 @default.
- B744b6f3582575a81aa0d38a6cd1bd44e annotatedTarget "A preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the CD30 antigen, with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD30 CAR T cells HSP-CAR30 specifically recognize and bind to CD30-expressing tumor cells, resulting in tumor cell lysis. CD30, a cell surface receptor and a member of the tumor necrosis factor (TNF) receptor superfamily, is transiently expressed on activated lymphocytes and is constitutively expressed in hematologic malignancies." @default.