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- B74898217e20804e3af15552500a51e81 NCIT_P378 "NCI" @default.
- B74898217e20804e3af15552500a51e81 type Axiom @default.
- B74898217e20804e3af15552500a51e81 annotatedProperty IAO_0000115 @default.
- B74898217e20804e3af15552500a51e81 annotatedSource NCIT_C83780 @default.
- B74898217e20804e3af15552500a51e81 annotatedTarget "A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Idrapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.