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- B74eae05abfdc196ad72ea596e9979eea NCIT_P378 "NCI" @default.
- B74eae05abfdc196ad72ea596e9979eea type Axiom @default.
- B74eae05abfdc196ad72ea596e9979eea annotatedProperty IAO_0000115 @default.
- B74eae05abfdc196ad72ea596e9979eea annotatedSource NCIT_C28825 @default.
- B74eae05abfdc196ad72ea596e9979eea annotatedTarget "A synthetic quinazoline derivative, Anagrelide reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)" @default.