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- B755fa43a0f3b9248fab72301e8509935 NCIT_P378 "NCI" @default.
- B755fa43a0f3b9248fab72301e8509935 type Axiom @default.
- B755fa43a0f3b9248fab72301e8509935 annotatedProperty IAO_0000115 @default.
- B755fa43a0f3b9248fab72301e8509935 annotatedSource NCIT_C460 @default.
- B755fa43a0f3b9248fab72301e8509935 annotatedTarget "An edetate and a chelating agent used in preparing radiopharmaceuticals. Pentetic acid (DTPA) has strong affinity for iron but also shows affinities for other heavy metals, thereby is used in the treatment of iron-storage disease and poisoning from heavy and radioactive metals. DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects. In addition, DTPA is used in radioimaing procedures when complexes with radioisotopes, ex., Tc 99m or In 111." @default.