Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B75a2258cc528ba6bf0520be406ebd692> ?p ?o ?g. }
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- B75a2258cc528ba6bf0520be406ebd692 NCIT_P378 "NCI" @default.
- B75a2258cc528ba6bf0520be406ebd692 type Axiom @default.
- B75a2258cc528ba6bf0520be406ebd692 annotatedProperty IAO_0000115 @default.
- B75a2258cc528ba6bf0520be406ebd692 annotatedSource NCIT_C165280 @default.
- B75a2258cc528ba6bf0520be406ebd692 annotatedTarget "A radioimmunoconjugate composed of the anti-CD38 monoclonal antibody (MoAb) OKT10-B10 labeled with the alpha-emitting radionuclide astatine (At) 211 (211At), with potential antineoplastic activity. Upon administration of astatine At 211 anti-CD38 MoAb OKT10-B10, the MoAb moiety targets and binds to CD38-expressing tumor cells, thereby delivering a cytotoxic dose of alpha radiation directly to the CD38-expressing tumor cells. CD38, a type II transmembrane glycoprotein and tumor-associated antigen (TAA), is present on various immune cells and in hematologic malignancies; its expression has been correlated with poor prognosis." @default.