Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B75e04a51fce59546ccd86eabfee2af7a> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B75e04a51fce59546ccd86eabfee2af7a NCIT_P378 "NCI" @default.
- B75e04a51fce59546ccd86eabfee2af7a type Axiom @default.
- B75e04a51fce59546ccd86eabfee2af7a annotatedProperty IAO_0000115 @default.
- B75e04a51fce59546ccd86eabfee2af7a annotatedSource NCIT_C104732 @default.
- B75e04a51fce59546ccd86eabfee2af7a annotatedTarget "An orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. Savolitinib selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c-Met protein. C-Met encodes the hepatocyte growth factor receptor tyrosine kinase and plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis; this protein is overexpressed or mutated in a variety of cancers." @default.