Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B7642222747e131c52891ca7a7591fbea> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B7642222747e131c52891ca7a7591fbea NCIT_P378 "NCI" @default.
- B7642222747e131c52891ca7a7591fbea type Axiom @default.
- B7642222747e131c52891ca7a7591fbea annotatedProperty IAO_0000115 @default.
- B7642222747e131c52891ca7a7591fbea annotatedSource NCIT_C65538 @default.
- B7642222747e131c52891ca7a7591fbea annotatedTarget "The S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell." @default.