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- B76c60f2033af2652f6babd43a3b1fd6f NCIT_P378 "NCI" @default.
- B76c60f2033af2652f6babd43a3b1fd6f type Axiom @default.
- B76c60f2033af2652f6babd43a3b1fd6f annotatedProperty IAO_0000115 @default.
- B76c60f2033af2652f6babd43a3b1fd6f annotatedSource NCIT_C1208 @default.
- B76c60f2033af2652f6babd43a3b1fd6f annotatedTarget "A nucleoside analog. Pyrazofurin potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting in cytotoxicity. This agent also causes a rapid depletion of the pyrimidine deoxynucleotide pool, thereby inhibiting DNA synthesis and cell replication. (NCI04)" @default.