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- B76e4723afb8a28292907256a7dcd9d5a NCIT_P378 "NCI" @default.
- B76e4723afb8a28292907256a7dcd9d5a type Axiom @default.
- B76e4723afb8a28292907256a7dcd9d5a annotatedProperty IAO_0000115 @default.
- B76e4723afb8a28292907256a7dcd9d5a annotatedSource NCIT_C72625 @default.
- B76e4723afb8a28292907256a7dcd9d5a annotatedTarget "A semisynthetic, broad-spectrum, beta-lactamase-resistant, third-generation cephalosporin with antibacterial activity. Cefditoren binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.