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- B78c35f72f4e3bdb773b8e26a29ed25de hasDbXref "Wikipedia:Nucleus_raphe_pallidus" @default.
- B78c35f72f4e3bdb773b8e26a29ed25de type Axiom @default.
- B78c35f72f4e3bdb773b8e26a29ed25de annotatedProperty IAO_0000115 @default.
- B78c35f72f4e3bdb773b8e26a29ed25de annotatedSource UBERON_0002157 @default.
- B78c35f72f4e3bdb773b8e26a29ed25de annotatedTarget "The nucleus raphe pallidus receives afferent connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Also, the pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei . The pallidus has recently been shown to be involved in the activation of a fever as an immunoreaction. It has been implied that the preoptic area is constantly inhibiting the raphe pallidus, especially the rostral portion, with GABA. When the preoptic area receives immune signals from the body, the inhibition stops and the rostral portion of the raphe pallidus excites the intermediolateral cell column, which induces a fever . The raphe pallidus has also been known to mediate the tachycardia response, an extremely high heart rate known to be incited by emotional or psychological stress. Microinjections of a GABA-a antagonist into the raphe pallidus, induces an increased heart rate. Conversely, microinjections of muscimol, a GABA-a agonist, inhibit tachycardia in rats under air-stress stimuli. In both of these cases, GABA is mediating two different sympathetic responses, so clearly the nucleus raphe pallidus is a far more a complex nucleus than previously thought. [WP,unvetted]." @default.