Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B7940a0a1d7a06eb9fade5fe6ac2957d8> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B7940a0a1d7a06eb9fade5fe6ac2957d8 NCIT_P378 "NCI" @default.
- B7940a0a1d7a06eb9fade5fe6ac2957d8 type Axiom @default.
- B7940a0a1d7a06eb9fade5fe6ac2957d8 annotatedProperty IAO_0000115 @default.
- B7940a0a1d7a06eb9fade5fe6ac2957d8 annotatedSource NCIT_C76034 @default.
- B7940a0a1d7a06eb9fade5fe6ac2957d8 annotatedTarget "A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefluprenam binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.