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- B794e6fb9014b8b19c8bd5ba839e4eb47 NCIT_P378 "NCI" @default.
- B794e6fb9014b8b19c8bd5ba839e4eb47 type Axiom @default.
- B794e6fb9014b8b19c8bd5ba839e4eb47 annotatedProperty IAO_0000115 @default.
- B794e6fb9014b8b19c8bd5ba839e4eb47 annotatedSource NCIT_C76172 @default.
- B794e6fb9014b8b19c8bd5ba839e4eb47 annotatedTarget "A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefozopran binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.