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- B7b4251f704bade6a0e4615dc0a36c63e NCIT_P378 "NCI" @default.
- B7b4251f704bade6a0e4615dc0a36c63e type Axiom @default.
- B7b4251f704bade6a0e4615dc0a36c63e annotatedProperty IAO_0000115 @default.
- B7b4251f704bade6a0e4615dc0a36c63e annotatedSource NCIT_C1051 @default.
- B7b4251f704bade6a0e4615dc0a36c63e annotatedTarget "A quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III (PDE III). Although the exact mechanism of action of is unknown, cilostazol and its metabolites appears to inhibit PDE III activity, thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. This results in an increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation." @default.