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- B7b701b576e9a87ede36c227c06c2c3cd hasDbXref "doi:10.1038/s41385-022-00565-0" @default.
- B7b701b576e9a87ede36c227c06c2c3cd type Axiom @default.
- B7b701b576e9a87ede36c227c06c2c3cd annotatedProperty comment @default.
- B7b701b576e9a87ede36c227c06c2c3cd annotatedSource CL_4030056 @default.
- B7b701b576e9a87ede36c227c06c2c3cd annotatedTarget "Umbrella cells are attached to sub-superficial cell layers via desmosomes, while tight junctions localized between superficial cells aid in forming a high-resistance barrier function. Another distinguishing feature of an umbrella cell type is the presence of subapical discoidal/fusiform-shaped vesicles contributing to the plasticity in urothelial cell surface area through a regulated process of endocytosis/exocytosis. It has been noted in at least some mammalian species that the urothelial umbrella cell type expresses UPK1A, UPK1B, UPK2 and UPK3A. Unlike intermediate and basal cells of the urothelium, CK17 is reported to be completely absent and p63 not expressed in umbrella cells." @default.