Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B7c665052d8ed1fe1502baca34c5dcc0b> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B7c665052d8ed1fe1502baca34c5dcc0b NCIT_P378 "NCI" @default.
- B7c665052d8ed1fe1502baca34c5dcc0b type Axiom @default.
- B7c665052d8ed1fe1502baca34c5dcc0b annotatedProperty IAO_0000115 @default.
- B7c665052d8ed1fe1502baca34c5dcc0b annotatedSource NCIT_C47519 @default.
- B7c665052d8ed1fe1502baca34c5dcc0b annotatedTarget "The hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation." @default.