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- B7cabfcc5a2b2fa7b7ca17e045309c44e NCIT_P378 "NCI" @default.
- B7cabfcc5a2b2fa7b7ca17e045309c44e type Axiom @default.
- B7cabfcc5a2b2fa7b7ca17e045309c44e annotatedProperty IAO_0000115 @default.
- B7cabfcc5a2b2fa7b7ca17e045309c44e annotatedSource NCIT_C47517 @default.
- B7cabfcc5a2b2fa7b7ca17e045309c44e annotatedTarget "The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins. Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels. Constriction of cerebral blood vessels caused by this agent may reduce the blood flow and pressure in cerebral arteries and may relieve the pain of vascular headaches." @default.