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- B7d5521c7553bd6704a6a9a6b8c248d88 NCIT_P378 "NCI" @default.
- B7d5521c7553bd6704a6a9a6b8c248d88 type Axiom @default.
- B7d5521c7553bd6704a6a9a6b8c248d88 annotatedProperty IAO_0000115 @default.
- B7d5521c7553bd6704a6a9a6b8c248d88 annotatedSource NCIT_C1099 @default.
- B7d5521c7553bd6704a6a9a6b8c248d88 annotatedTarget "A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation." @default.