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- B7e0bfbc52df0c77492c00d499033bbcc NCIT_P378 "NCI" @default.
- B7e0bfbc52df0c77492c00d499033bbcc type Axiom @default.
- B7e0bfbc52df0c77492c00d499033bbcc annotatedProperty IAO_0000115 @default.
- B7e0bfbc52df0c77492c00d499033bbcc annotatedSource NCIT_C52184 @default.
- B7e0bfbc52df0c77492c00d499033bbcc annotatedTarget "An orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, inducing cell cycle arrest, and inducing apoptosis." @default.